Title : Serum and epidermal growth factor transiently depolarize quiescent BSC-1 epithelial cells.

Pub. Date : 1982 Dec

PMID : 6984193






1 Functional Relationships(s)
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1 Initial results show that (i) there is no significant difference in membrane potential between growing and quiescent cells, (ii) addition of epidermal growth factor or serum to quiescent BSC-1 cells induces a brief and transient depolarization, (iii) the mitogenic response of BSC-1 cells to epidermal growth factor and the transient depolarization show similar concentration dependences, and (iv) serum addition to quiescent BSC-1 cells induces a sustained increase in Na+ influx that is electroneutral and amiloride sensitive. Amiloride epidermal growth factor Homo sapiens