Title : Effects of drugs and sterols on cholesterol 7 alpha-hydroxylase activity in rat liver microsomes.

Pub. Date : 1983 Jan

PMID : 6833879






1 Functional Relationships(s)
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1 The activity of cholesterol 7alpha-hydroxylase was also significantly inhibited by 7beta-hydroxycholesterol (38%) and 7-ketocholesterol (35%) at concentrations of 1 micro M, and by 10 micro M 7alpha-hydroxycholesterol (35%), 25alpha-hydroxycholesterol (32%), and 5-cholenic acid-3beta-ol (27%). 7-ketocholesterol cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus