Title : Effects of vinblastine on malondialdehyde formation, serotonin release and aggregation in human platelets.

Pub. Date : 1982 Jul 30

PMID : 6811295






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Malondialdehyde formation, aggregation and [14C]serotonin release caused by threshold doses of thrombin were reduced but not abolished by 100 muM vinblastine; 30-100 muM vinblastine abolished ADP- and PGAP-induced malondialdehyde formation and [14C]serotonin released and transformed ADP- and PGAP-induced irreversible aggregation to a diminished reversible response. Carbon-14 coagulation factor II, thrombin Homo sapiens
2 Malondialdehyde formation, aggregation and [14C]serotonin release caused by threshold doses of thrombin were reduced but not abolished by 100 muM vinblastine; 30-100 muM vinblastine abolished ADP- and PGAP-induced malondialdehyde formation and [14C]serotonin released and transformed ADP- and PGAP-induced irreversible aggregation to a diminished reversible response. Carbon-14 coagulation factor II, thrombin Homo sapiens