Title : Development of different electrophysiological mechanisms for muscarinic inhibition of atria and ventricles.

Pub. Date : 1984 Aug

PMID : 6745450






2 Functional Relationships(s)
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1 The negative inotropic effect of acetylcholine (ACh) in atrial muscle can be accounted for by a decrease of a voltage- and time-dependent slow inward current (Isi) carried by Ca2+/Na+ and an increase of outward time-dependent current carried by K+ (IK1) through inwardly rectifying channels. Acetylcholine IKAROS family zinc finger 1 Homo sapiens
2 The negative inotropic effect of acetylcholine (ACh) in atrial muscle can be accounted for by a decrease of a voltage- and time-dependent slow inward current (Isi) carried by Ca2+/Na+ and an increase of outward time-dependent current carried by K+ (IK1) through inwardly rectifying channels. Acetylcholine IKAROS family zinc finger 1 Homo sapiens