Pub. Date : 1983 Dec 1
PMID : 6661183
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of the condensing component of chicken liver fatty acid synthase by iodoacetamide and 5,5"-dithiobis-(2-nitrobenzoic acid). | Iodoacetamide | fatty acid synthase | Gallus gallus |
| 2 | Chicken liver fatty acid synthase is inhibited by the thiol-modifying reagents 5,5"-dithiobis-(2-nitrobenzoic acid) and iodoacetamide. | Iodoacetamide | fatty acid synthase | Gallus gallus |
| 3 | The results obtained with iodoacetamide show that in the dimeric fatty acid synthase modification of one cysteine-SH condensing site and/or one pantetheine-SH site per dimer is sufficient to affect inhibition of condensing activity and the activity for fatty acid synthesis, and are in accord with a recently proposed model for the mechanism of action of animal fatty acid synthases [Kumar (1982) J. Theor. | Iodoacetamide | fatty acid synthase | Gallus gallus |