Title : Beta 2-microglobulin and its binding activity in serum from patients with SLE.

Pub. Date : 1984 Apr

PMID : 6370153






7 Functional Relationships(s)
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1 Repeated determinations of beta 2-microglobulin (beta 2m) and beta 2-microglobulin binding activity (beta 2m ba) in serum were performed during a follow-up of 23 patients with SLE. Barium beta-2-microglobulin Homo sapiens
2 The beta 2m ba was determined by precipitation of 125I-labelled beta 2m with polyethylene glycol. Barium beta-2-microglobulin Homo sapiens
3 The beta 2m ba was determined by precipitation of 125I-labelled beta 2m with polyethylene glycol. Barium beta-2-microglobulin Homo sapiens
4 Increased beta 2m ba was found in 26% of the SLE patients with the 90th percentile in 40 healthy subjects being taken as the upper normal limit. Barium beta-2-microglobulin Homo sapiens
5 Patients with systemic lupus erythematosus (SLE), suffering exacerbation of their disease, had a higher mean beta 2m ba than those with less active disease. Barium beta-2-microglobulin Homo sapiens
6 Variations of the serum beta 2m ba occurred especially in patients with active disease but did not seem to reflect the clinical course. Barium beta-2-microglobulin Homo sapiens
7 The beta 2m ba was recovered in the IgG peak when SLE serum was subjected to gel chromatography on Sephadex G-200. Barium beta-2-microglobulin Homo sapiens