Pub. Date : 1984 Apr 12-18
PMID : 6324004
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Two apparently distinct mechanisms have now been identified for enhancing 125I-vWF interaction with stimulated platelets: one is induced by ristocetin and apparently mediated by platelet membrane glycoprotein Ib (GPIb); a second mechanism has been identified more recently and is induced by the physiological stimuli ADP and thrombin. | Adenosine Diphosphate | von Willebrand factor | Homo sapiens |
| 2 | As ADP and thrombin are released at sites of platelet accumulation, it is possible that these agonists regulate the vWF-platelet interactions in vivo. | Adenosine Diphosphate | von Willebrand factor | Homo sapiens |
| 3 | Thus, in addition to its role in coagulation and platelet aggregation, fibrinogen influences the binding of vWF to thrombin- and ADP-stimulated platelets. | Adenosine Diphosphate | von Willebrand factor | Homo sapiens |