Title : The granulocyte response to the phosphodiesterase inhibitor RO 20-1724 in asthma.

Pub. Date : 1981 Jan

PMID : 6256424






2 Functional Relationships(s)
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1 Isolated human granulocytes secrete the lysosomal enzyme beta glucuronidase when incubated with complement-activated zymosan particles. Zymosan glucuronidase beta Homo sapiens
2 We found that the potent phosphodiesterase inhibitor, RO 20-1724, inhibited zymosan-stimulated beta glucuronidase release from granulocytes in a dose-dependent fashion (10(-8) to 10(-4) M). Zymosan glucuronidase beta Homo sapiens