Title : Role of the renin-angiotensin system in enhancing the aldosterone response to adenocorticotropin during acute sodium depletion in normal subjects.

Pub. Date : 1980 Nov

PMID : 6252230






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1 The role of the renin-angiotensin system in enhancing aldosterone responsiveness to ACTH during acute sodium depletion was studied in 14 healthy medical students. Sodium proopiomelanocortin Homo sapiens
2 The administration of ACTH, but not of vehicle, produced significant increases in plasma aldosterone in both control and acute sodium-depleted subjects. Sodium proopiomelanocortin Homo sapiens
3 However, the ACTH-induced increases in plasma aldosterone and their maximal net and percent increments during acute sodium depletion were significantly greater than control values. Sodium proopiomelanocortin Homo sapiens