PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6252230-1 1980 The role of the renin-angiotensin system in enhancing aldosterone responsiveness to ACTH during acute sodium depletion was studied in 14 healthy medical students. Sodium 102-108 proopiomelanocortin Homo sapiens 84-88 6252230-5 1980 The administration of ACTH, but not of vehicle, produced significant increases in plasma aldosterone in both control and acute sodium-depleted subjects. Sodium 127-133 proopiomelanocortin Homo sapiens 22-26 6252230-6 1980 However, the ACTH-induced increases in plasma aldosterone and their maximal net and percent increments during acute sodium depletion were significantly greater than control values. Sodium 116-122 proopiomelanocortin Homo sapiens 13-17