Pub. Date : 1984 Feb 28
PMID : 6202020
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Selective PF4 release in vitro induced by heparin and related glycosaminoglycans (GAGs)--correlation with beta-TG release and platelet aggregation. | Glycosaminoglycans | platelet factor 4 | Homo sapiens |
| 2 | Selective PF4 release in vitro induced by heparin and related glycosaminoglycans (GAGs)--correlation with beta-TG release and platelet aggregation. | Glycosaminoglycans | platelet factor 4 | Homo sapiens |
| 3 | We studied human platelet aggregation and beta-TG/PF4 release induced by heparin and related GAGs in vitro both in normal PRP and in PRP after aspirin. | Glycosaminoglycans | platelet factor 4 | Homo sapiens |
| 4 | In our experimental conditions, heparin and related GAGs always caused PF4 release in vitro from normal platelets, whether or not there was measurable platelet aggregation in the aggregometer. | Glycosaminoglycans | platelet factor 4 | Homo sapiens |
| 5 | Therefore, while beta-TG release in vitro seems to correlate with platelet aggregating activity of heparin, the selective PF4 release, caused by heparin and related GAGs also in conditions in which neither platelet aggregation nor beta-TG are measurable, is probably associated with the high affinity of PF4 for heparin. | Glycosaminoglycans | platelet factor 4 | Homo sapiens |
| 6 | The degree of affinity of GAGs for PF4 (heparin greater than DeS greater than HS) seems to correlate with PF4 release. | Glycosaminoglycans | platelet factor 4 | Homo sapiens |
| 7 | The degree of affinity of GAGs for PF4 (heparin greater than DeS greater than HS) seems to correlate with PF4 release. | Glycosaminoglycans | platelet factor 4 | Homo sapiens |
| 8 | Moreover, the significant reduction in PF4 release in vitro after aspirin suggests that GAGs-induced PF4 release is related to a cyclooxygenase-dependent activation process. | Glycosaminoglycans | platelet factor 4 | Homo sapiens |
| 9 | Moreover, the significant reduction in PF4 release in vitro after aspirin suggests that GAGs-induced PF4 release is related to a cyclooxygenase-dependent activation process. | Glycosaminoglycans | platelet factor 4 | Homo sapiens |