Pub. Date : 1983 Jul 1
PMID : 6193602
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When PPS was added to heparin containing plasma it was observed to completely inhibit heparin at low concentrations (2:1 on a weight to weight basis) when measured in the thrombin and prothrombin time but not in the KCCT. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 2 | The antiheparin effect of PPS was also observed in a purified system in obviating the heparin potentiation of the rate of inhibition of thrombin by antithrombin III. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |
| 3 | Observations showed that at higher concentrations of PPS it acted by directly inhibiting thrombin without the intervention of antithrombin III but also to potentiate the rate of fibrin monomer polymerization. | Pentosan Sulfuric Polyester | coagulation factor II, thrombin | Homo sapiens |