Title : Role of methotrexate polyglutamylation and cellular energy metabolism in inhibition of methotrexate binding to dihydrofolate reductase by 5-formyltetrahydrofolate in Ehrlich ascites tumor cells in vitro.

Pub. Date : 1983 Jun

PMID : 6189586






1 Functional Relationships(s)
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1 However, glucose or azide increased the fraction of dihydrofolate reductase associated with methotrexate and abolished the effect of tetrahydrofolates on this intracellular component. Azides dihydrofolate reductase Mus musculus