Title : Adenosine-dependent activation of tyrosine hydroxylase is defective in adenosine kinase-deficient PC12 cells.

Pub. Date : 1984 Aug

PMID : 6146982






2 Functional Relationships(s)
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1 PIA (10 microM) is as effective as cholera toxin or dibutyryl cAMP in activating TyrOHase in wild-type cells. Cyclic AMP tyrosine hydroxylase Rattus norvegicus
2 These studies with kinase-deficient PC12 cells provide genetic evidence that adenosine-dependent activation of TyrOHase is mediated by acute increases in cAMP. Cyclic AMP tyrosine hydroxylase Rattus norvegicus