Title : Effect of liposome composition on the activity of detergent-solubilized acylcoenzyme A: cholesterol acyltransferase.

Pub. Date : 1982 Jul

PMID : 6126513






5 Functional Relationships(s)
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1 When this microsomal extract was combined with liposomes composed of cholesterol and egg phosphatidylcholine, the ACAT activity increased 5.4- to 6.7-fold. Phosphatidylcholines acetyl-Coenzyme A acetyltransferase 1 Mus musculus
2 ACAT activity increased 2.9-fold when the phosphatidylcholine content of the liposomes was raised from 0.5 to 5.0 mumol/mg microsomal protein. Phosphatidylcholines acetyl-Coenzyme A acetyltransferase 1 Mus musculus
3 ACAT activity was five times higher when the liposomes were prepared from dioleoylphosphatidylcholine than from saturated phosphatidylcholines, including hydrogenated egg yolk, dimyristoyl or dipalmitoyl phosphatidylcholine. Phosphatidylcholines acetyl-Coenzyme A acetyltransferase 1 Mus musculus
4 Likewise, the ACAT activity with liposomes made from soybean or egg yolk phosphatidylcholine was almost 3.5-fold greater than with those prepared from the saturated phosphatidylcholines. Phosphatidylcholines acetyl-Coenzyme A acetyltransferase 1 Mus musculus
5 Likewise, the ACAT activity with liposomes made from soybean or egg yolk phosphatidylcholine was almost 3.5-fold greater than with those prepared from the saturated phosphatidylcholines. Phosphatidylcholines acetyl-Coenzyme A acetyltransferase 1 Mus musculus