Title : Evidence for an ester bond between thrombin and heparin cofactor.

Pub. Date : 1976 Feb 29

PMID : 60792






2 Functional Relationships(s)
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1 The nature of the binding between thrombin and the inhibitor is studied by treatment of the complex with 6 M guanidinium chloride, hydroxylamine, and dilute alkali. Hydroxylamine coagulation factor II, thrombin Homo sapiens
2 Treatment of dodecyl sulfate-denatured complex with hydroxylamine results in dissociation of the complex to yield free thrombin and heparin cofactor. Hydroxylamine coagulation factor II, thrombin Homo sapiens