Pub. Date : 1969 Oct
PMID : 5346365
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It is suggested that each of the four tyrosyl groups in insulin has a different environment: Tyr-A-14 is fully exposed to the solvent; Tyr-A-19 is sterically influenced by the environmental structure, possibly by the vicinity of a disulphide interchain bond; Tyr-B-16 is embedded into a non-polar area whose stability is virtually independent of the molecular conformation; Tyr-B-26 is probably in a situation similar to Tyr-B-16 with the difference that its non-polar environment depends on the preservation of the native structure. | disulphide | insulin | Homo sapiens |