Pub. Date : 1973 Jan
PMID : 4629909
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Methimazole stimulates deiodination by MPO and H(2)O(2) but inhibits this reaction when MPO is replaced by lactoperoxidase or horseradish peroxidase.Intact human leukocytes, in the resting state, degrade T(4) and T(3) slowly: degradation, however, is increased markedly during phagocytosis of preopsonized particles. | Methimazole | myeloperoxidase | Homo sapiens |
| 2 | Methimazole stimulates deiodination by MPO and H(2)O(2) but inhibits this reaction when MPO is replaced by lactoperoxidase or horseradish peroxidase.Intact human leukocytes, in the resting state, degrade T(4) and T(3) slowly: degradation, however, is increased markedly during phagocytosis of preopsonized particles. | Methimazole | myeloperoxidase | Homo sapiens |
| 3 | Methimazole inhibits the formation of iodinated origin material by both normal and MPO-deficient leukocytes. | Methimazole | myeloperoxidase | Homo sapiens |