Title : The effect of carbon dioxide on the intracellular pH and buffering power of snail neurones.

Pub. Date : 1976 Mar

PMID : 4614






7 Functional Relationships(s)
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1 The effects on pHi of CO2 applied externally and HCO3-, H+ and NH4+ injected iontophoretically, were investigated. Carbon Dioxide glucose-6-phosphate isomerase Homo sapiens
2 Exposure to Ringer, pH 7-5, equilibrated with 2-2% CO2 caused a rapid, but only transient, fall in pHi. Carbon Dioxide glucose-6-phosphate isomerase Homo sapiens
3 When external CO2 was removed, pHi rapidly increased, and then slowly returned to normal. Carbon Dioxide glucose-6-phosphate isomerase Homo sapiens
4 The pHi changes with CO2 application or removal gave a calculated intracellular buffer value of about 30 m-equiv H+/pH unit per litre. Carbon Dioxide glucose-6-phosphate isomerase Homo sapiens
5 The pHi responses to CO2 application, CO2 removal and HCO3- injection were slowed by the carbonic anhydrase inhibitor acetazolamide. Carbon Dioxide glucose-6-phosphate isomerase Homo sapiens
6 The pHi responses to CO2 application, CO2 removal and HCO3- injection were slowed by the carbonic anhydrase inhibitor acetazolamide. Carbon Dioxide glucose-6-phosphate isomerase Homo sapiens
7 In CO2 Ringer pHi fell less and recovered faster than in CO2-free Ringer. Carbon Dioxide glucose-6-phosphate isomerase Homo sapiens