Title : Cobra venom phospholipase A2 inhibition by manoalide. A novel type of phospholipase inhibitor.

Pub. Date : 1985 Jun 25

PMID : 3997864






1 Functional Relationships(s)
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1 For a given concentration of manoalide, the inhibition of phospholipase A2 activity toward dipalmitoylphosphatidylcholine/Triton X-100 mixed micelles is time-dependent and plateaus at about 85% inhibition of the initial velocity even after extensive preincubation. 1,2-Dipalmitoylphosphatidylcholine phospholipase A2 group IB Homo sapiens