Pub. Date : 1979
PMID : 398128
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Neutropenia following prolonged inhalation of nitrous oxide seems to be caused by a different mechanism, in which the cobalt in B12 is oxidised to the trivalent form by chemical reaction with nitrous oxide. | Nitrous Oxide | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
| 2 | Neutropenia following prolonged inhalation of nitrous oxide seems to be caused by a different mechanism, in which the cobalt in B12 is oxidised to the trivalent form by chemical reaction with nitrous oxide. | Nitrous Oxide | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
| 3 | B12 is thereby inactivated and this interferes with folate metabolism and thymidine synthesis: the effect may be detected after only a few hours in vivo exposure of mammals to 50% nitrous oxide. | Nitrous Oxide | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |