Title : Modification of histidines in human prothrombin. Effect on the interaction of fibrinogen with thrombin from diethyl pyrocarbonate-modified prothrombin.

Pub. Date : 1985 Apr 25

PMID : 3886645






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Modification of histidines in human prothrombin. Histidine coagulation factor II, thrombin Homo sapiens
2 Statistical analysis of residual enzyme activity and extent of modification indicates that among 7 histidyl residues modified per molecule, there is 1 essential histidine (not in the active site) involved in the potential fibrinogen-clotting activity of prothrombin. Histidine coagulation factor II, thrombin Homo sapiens