Pub. Date : 1985 Sep
PMID : 3876600
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Fibronectin binds to complement-coated agarose beads and increases their association to mouse macrophages. | Sepharose | fibronectin 1 | Mus musculus |
| 2 | We have studied the binding of fibronectin to complement (C3b, C3bi, C3d)-coated agarose beads and its effect on cell association of such beads to mouse macrophages. | Sepharose | fibronectin 1 | Mus musculus |
| 3 | Fibronectin bound to agarose beads preincubated in human serum, whereas no binding occurred after preincubation of the beads with complement-inactivated (50 degrees C for 20 min or ethylenediaminetetraacetic acid) sera. | Sepharose | fibronectin 1 | Mus musculus |
| 4 | A similar amount of fibronectin bound to agarose beads coated with equimolar amounts of C3b, C3bi, or C3d, suggesting that the common domain C3d carries the main binding site(s) for fibronectin. | Sepharose | fibronectin 1 | Mus musculus |
| 5 | Preincubation of serum-treated and trypsinized agarose beads with fibronectin led to an increased association (22%) of such beads to mouse macrophages. | Sepharose | fibronectin 1 | Mus musculus |
| 6 | The results indicate that fibronectin promotes binding of complement-coated agarose beads to mouse macrophages, whereas the ingestion of the beads is mediated via complement C3 receptors. | Sepharose | fibronectin 1 | Mus musculus |