Title : Does the pentose cycle play a major role for NADPH supply in the heart?

Pub. Date : 1986 Oct

PMID : 3790254






1 Functional Relationships(s)
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1 Even under conditions of increased NADPH requirements (infusion of tert-butylhydroperoxide) and a diminished 14CO2 production from glucose via the citrate cycle (in the presence of oleate as additional substrate) or enhanced activity of glucose-6-phosphate dehydrogenase (pretreatment with isoproterenol), a substrate flux through the pentose cycle was not detectable. Pentoses glucose-6-phosphate dehydrogenase Rattus norvegicus