| Protein Name | glucose-6-phosphate dehydrogenase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24377 |
| Gene Symbol | G6pd |
| UniProt | P05370 (G6PD_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
528
Total Number of Articles : 787 |
Description |
glucose-6-phosphate dehydrogenase |
| Gene Summary |
Enables D-glucose binding activity; NADP binding activity; and glucose-6-phosphate dehydrogenase activity. Involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development; pentose-phosphate shunt, oxidative branch; and positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Predicted to be located in centriolar satellite; cytoplasm; and cytoplasmic side of plasma membrane. Predicted to be active in cytosol. Used to study cataract and transient cerebral ischemia. Biomarker of several diseases, including artery disease (multiple); hepatic encephalopathy; hyperhomocysteinemia; liver disease (multiple); and phenylketonuria. Human ortholog(s) of this gene implicated in anemia (multiple); cerebrovascular disease; diabetes mellitus; malaria (multiple); and neonatal jaundice. Orthologous to human G6PD (glucose-6-phosphate dehydrogenase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |