Title : Phorbol esters modulate thrombin-operated calcium mobilisation and dense granule release in human platelets.

Pub. Date : 1986 May 29

PMID : 3708006






1 Functional Relationships(s)
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1 Preincubation of the platelets with either TPA or 12-deoxyphorbol 13-phenylacetate, but not the parent, 4-beta-phorbol, produced a dose-dependent inhibition of the elevation of [Ca2+]i and 5-hydroxytryptamine release induced by human alpha-thrombin. 12-deoxyphorbolphenylacetate coagulation factor II, thrombin Homo sapiens