Title : Cadmium binding and metal cluster formation in metallothionein: a differential modification study.

Pub. Date : 1986 Apr 22

PMID : 3707924






2 Functional Relationships(s)
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1 The formation of these oligonuclear complexes designated as Cd4 and Cd3 clusters has now been monitored in MT reconstituted with varying amounts of Cd by using differential chemical modification of Cys with [14C]iodoacetamide. Cysteine CD4 molecule Homo sapiens
2 The extent of labeling of the different Cys in Cd7-MT indicates that the ligands of the Cd3 cluster are 3 times as accessible to iodoacetamide than those of the Cd4 cluster, suggesting a greater thermodynamic or kinetic stability of the latter. Cysteine CD4 molecule Homo sapiens