Title : The effect of hydroxyurea on the expression of the common fragile site at 3p14.

Pub. Date : 1987 Oct

PMID : 3681903






2 Functional Relationships(s)
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1 We have studied the effect of HU on the common fragile site at 3p14 (FRA3B) and have found that G2 treatment with HU increased not only the frequency of chromosomal aberration but also the expression of FRA3B in both complete and folate deficient media. Folic Acid fragile histidine triad diadenosine triphosphatase Homo sapiens
2 There is a synergistic effect between HU and growth in folate deficient medium on the induction of FRA3B. Folic Acid fragile histidine triad diadenosine triphosphatase Homo sapiens