Title : TGF-β promotes pericyte-myofibroblast transition in subretinal fibrosis through the Smad2/3 and Akt/mTOR pathways.

Pub. Date : 2022 May

PMID : 35624154






1 Functional Relationships(s)
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1 Primary mouse choroidal GFP-positive pericytes were treated with TGF-beta2 in combination with siRNAs targeting Smad2/3, the Akt inhibitor MK2206 or the mTOR inhibitor rapamycin to examine cell proliferation, migration, and differentiation into myofibroblasts. Sirolimus mechanistic target of rapamycin kinase Mus musculus