Title : OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells.

Pub. Date : 2022

PMID : 35619904






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Results: Knocking out BRCA1 in triple-negative breast cancer cell lines causes hypersensitivity to the OGG1 inhibitor TH5487. TH5487 8-oxoguanine DNA glycosylase Homo sapiens