Pub. Date : 2022 May
PMID : 35609321
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pirfenidone attenuates cardiac hypertrophy against isoproterenol by inhibiting activation of the janus tyrosine kinase-2/signal transducer and activator of transcription 3 (JAK-2/STAT3) signaling pathway. | pirfenidone | signal transducer and activator of transcription 3 | Mus musculus |
| 2 | Pirfenidone attenuates cardiac hypertrophy against isoproterenol by inhibiting activation of the janus tyrosine kinase-2/signal transducer and activator of transcription 3 (JAK-2/STAT3) signaling pathway. | pirfenidone | signal transducer and activator of transcription 3 | Mus musculus |
| 3 | Lastly, the promoted expression levels of p-JAK-2/JAK-2 and p-STAT3/STAT-3 in the cardiac tissues of ISO-challenged mice were significantly repressed by Pirfenidone or SPI. | pirfenidone | signal transducer and activator of transcription 3 | Mus musculus |
| 4 | Lastly, the promoted expression levels of p-JAK-2/JAK-2 and p-STAT3/STAT-3 in the cardiac tissues of ISO-challenged mice were significantly repressed by Pirfenidone or SPI. | pirfenidone | signal transducer and activator of transcription 3 | Mus musculus |