PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35609321-0 2022 Pirfenidone attenuates cardiac hypertrophy against isoproterenol by inhibiting activation of the janus tyrosine kinase-2/signal transducer and activator of transcription 3 (JAK-2/STAT3) signaling pathway. pirfenidone 0-11 signal transducer and activator of transcription 3 Mus musculus 97-171 35609321-0 2022 Pirfenidone attenuates cardiac hypertrophy against isoproterenol by inhibiting activation of the janus tyrosine kinase-2/signal transducer and activator of transcription 3 (JAK-2/STAT3) signaling pathway. pirfenidone 0-11 signal transducer and activator of transcription 3 Mus musculus 179-184 35609321-7 2022 Lastly, the promoted expression levels of p-JAK-2/JAK-2 and p-STAT3/STAT-3 in the cardiac tissues of ISO-challenged mice were significantly repressed by Pirfenidone or SPI. pirfenidone 153-164 signal transducer and activator of transcription 3 Mus musculus 62-67 35609321-7 2022 Lastly, the promoted expression levels of p-JAK-2/JAK-2 and p-STAT3/STAT-3 in the cardiac tissues of ISO-challenged mice were significantly repressed by Pirfenidone or SPI. pirfenidone 153-164 signal transducer and activator of transcription 3 Mus musculus 68-74