Title : Mechanical Activation of the β2-Adrenergic Receptor by Meningococcus: A Historical and Future Perspective Analysis of How a Bacterial Probe Can Reveal Signalling Pathways in Endothelial Cells, and a Unique Mode of Receptor Activation Involving Its N-Terminal Glycan Chains.

Pub. Date : 2022

PMID : 35586623






1 Functional Relationships(s)
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1 Once bound to the N-terminal glycans of the beta2-adrenergic receptor, meningococcus provides a mechanical stimulation that induces the biased activation of beta-arrestin-mediated signalling pathways. n-terminal glycans adrenoceptor beta 2 Homo sapiens