Pub. Date : 2022 May 17
PMID : 35580917
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Vinpocetine enhances cisplatin sensitivity of non-small cell lung cancer cells by reducing the nuclear factor erythroid 2-related factor 2 signaling. | vinpocetine | NFE2 like bZIP transcription factor 2 | Homo sapiens |
2 | In addition, treatment with vinpocetine suppressed protein expression of Nrf2 and inhibited messenger RNA levels of heme oxygenase 1 and NAD(P)H dehydrogenase quinone 1 induced by cisplatin. | vinpocetine | NFE2 like bZIP transcription factor 2 | Homo sapiens |
3 | Interestingly, the overexpression of Nrf2 abolished the antiproliferative effects of vinpocetine on NSCLC cells. | vinpocetine | NFE2 like bZIP transcription factor 2 | Homo sapiens |
4 | Vinpocetine enhances cisplatin sensitivity of NSCLC cells in part by suppressing Nrf2 signaling. | vinpocetine | NFE2 like bZIP transcription factor 2 | Homo sapiens |