Title : TFEB controls integrin-mediated endothelial cell adhesion by the regulation of cholesterol metabolism.

Pub. Date : 2022 May 11

PMID : 35545719






1 Functional Relationships(s)
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1 We show that TFEB favors ECM adhesion turnover by promoting the transcription of genes that drive the synthesis of cholesterol, which promotes the aggregation of caveolin-1, and the caveolin-dependent endocytosis of integrin beta1. Cholesterol caveolin 1 Homo sapiens