Title : Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver disease.

Pub. Date : 2022 Jun

PMID : 35537354






1 Functional Relationships(s)
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1 The nutritionally essential precursors alpha-linolenic acid (C18:3n-3; ALA) and linoleic acid (C18:2n-6; LA) are subjected to desaturation by Delta6D/Delta5D desaturases and elongation by elongases 2/5, enzymes that are induced by insulin and repressed by PUFA. alpha-Linolenic Acid insulin Homo sapiens