Title : Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia.

Pub. Date : 2022 May 9

PMID : 35533259






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A subset of heparin-treated patients produces detectable levels of antibodies against complexes of heparin bound to circulating platelet factor 4 (PF4). Heparin platelet factor 4 Homo sapiens
2 A subset of heparin-treated patients produces detectable levels of antibodies against complexes of heparin bound to circulating platelet factor 4 (PF4). Heparin platelet factor 4 Homo sapiens
3 Using a genome-wide association study (GWAS) approach, we aimed to identify genetic variants associated with anti-PF4/heparin antibodies that account for the variable antibody response seen in HIT. Heparin platelet factor 4 Homo sapiens