Title : Canonical insulin signaling is not significantly impaired in early stages of depression.

Pub. Date : 2022 May 7

PMID : 35524821






2 Functional Relationships(s)
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Protein Name
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1 The first node (pS312-IRS-1, pY-IRS-1) and downstream pathway which affects glucose and lipid homeostasis (phosphorylated proteins: pS473-AKT, pS9-GSK3beta, pS2448-mTOR, pT389-p70S6K; total proteins AKT, GSK3beta, mTOR, p70S6K) were analyzed by electrochemiluminescence (ECL) in neuronal extracellular vesicles (nEVs) enriched for L1 neural cell adhesion molecule (L1CAM) expression. Glucose AKT serine/threonine kinase 1 Homo sapiens
2 The first node (pS312-IRS-1, pY-IRS-1) and downstream pathway which affects glucose and lipid homeostasis (phosphorylated proteins: pS473-AKT, pS9-GSK3beta, pS2448-mTOR, pT389-p70S6K; total proteins AKT, GSK3beta, mTOR, p70S6K) were analyzed by electrochemiluminescence (ECL) in neuronal extracellular vesicles (nEVs) enriched for L1 neural cell adhesion molecule (L1CAM) expression. Glucose AKT serine/threonine kinase 1 Homo sapiens