Pub. Date : 2022 Apr
PMID : 35510231
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Taken together, our preliminary investigations suggested that the rational deuteration of dronedarone at its benzofuran ring reduces aberrant cytochrome P450 3A4/5-mediated bioactivation, which attenuated its mitochondrial toxicity in human hepatic HepG2 cells. | benzofuran | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |