Title : Single-nucleotide polymorphisms and the effectiveness of taxane-based chemotherapy in premenopausal breast cancer: a population-based cohort study in Denmark.

Pub. Date : 2022 Apr 30

PMID : 35501422






2 Functional Relationships(s)
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1 CONCLUSION: Docetaxel effectiveness was influenced by SNPs in GSTP1, CYP3A, and SLCO1B1 in premenopausal women with non-distant metastatic breast cancer, likely related to altered docetaxel pharmacokinetics. Docetaxel solute carrier organic anion transporter family member 1B1 Homo sapiens
2 CONCLUSION: Docetaxel effectiveness was influenced by SNPs in GSTP1, CYP3A, and SLCO1B1 in premenopausal women with non-distant metastatic breast cancer, likely related to altered docetaxel pharmacokinetics. Docetaxel solute carrier organic anion transporter family member 1B1 Homo sapiens