Title : Microbiota-mediated skewing of tryptophan catabolism modulates CD4+ T cells in lupus-prone mice.

Pub. Date : 2022 May 20

PMID : 35494242






1 Functional Relationships(s)
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1 Functionally, tryptophan and its microbial product tryptamine increased T cell metabolism and mTOR activation, while kynurenine promoted interferon gamma production, all of which have been associated with lupus. Kynurenine interferon gamma Mus musculus