Title : Trough plasma nevirapine levels, immunologic and virologic responses in composite CYP2B6*6/*18 HIV-infected adult Nigerian patients.

Pub. Date : 2022 Jul

PMID : 35484635






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Composite CYP2B6*6/*18 genotype was significantly associated with trough plasma nevirapine levels (geometric mean (standard deviation): 4482 ng/ml (1349) of normal metabolizers vs. 4632 ng/ml (1793) of intermediate metabolizers vs. 6229 ng/ml (2549) of poor metabolizers; P < 0.001), but not the plasma HIV RNA levels, absolute lymphocyte and CD4+ T lymphocyte counts. Nevirapine cytochrome P450 family 2 subfamily B member 6 Homo sapiens
2 Composite CYP2B6*6/*18 genotype correlated with plasma nevirapine levels but not immunologic and virologic responses. Nevirapine cytochrome P450 family 2 subfamily B member 6 Homo sapiens