Title : Biophysical characterization as a tool to predict amyloidogenic and toxic properties of amyloid-β42 peptides.

Pub. Date : 2022 Jun

PMID : 35466397






1 Functional Relationships(s)
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1 Here, we tested recombinantly expressed Abeta42 (Asp1 to Ala42) against synthetic Abeta42 from different suppliers using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS), circular dichroism (CD) spectroscopy, thioflavin T aggregation, surface plasmon resonance and MTT cell viability assays. thioflavin T beta-secretase 2 Homo sapiens