Title : Sirtuin 3 Dependent and Independent Effects of NAD+ to Suppress Vascular Inflammation and Improve Endothelial Function in Mice.

Pub. Date : 2022 Apr 2

PMID : 35453391

1 Functional Relationships(s)
Compound Name
Protein Name
1 In human umbilical vein endothelial cells, SIRT3 silencing potentiated the induction of inflammatory factors by IL-1beta, including VCAM-1, ICAM-1, and MCP1, and the impairment of mitochondrial respiration, both of which were alleviated by NAD+ treatment. NAD sirtuin 3 Homo sapiens