Title : New steroidal alkaloids with anti-inflammatory and analgesic effects from Veratrum grandiflorum.

Pub. Date : 2022 Jul 15

PMID : 35452774






2 Functional Relationships(s)
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1 Anti-inflammatory test indicated that steroidal alkaloids could decrease the expression of cyclooxygenase-2 (COX-2), interleukin-1beta (IL-1beta), and tumor necrosis factor alpha (TNF-alpha) in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells at a concentration of 5.0 mug/ml in vitro, comparable to DXM. Alkaloids tumor necrosis factor Mus musculus
2 Anti-inflammatory test indicated that steroidal alkaloids could decrease the expression of cyclooxygenase-2 (COX-2), interleukin-1beta (IL-1beta), and tumor necrosis factor alpha (TNF-alpha) in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells at a concentration of 5.0 mug/ml in vitro, comparable to DXM. Alkaloids tumor necrosis factor Mus musculus