Title : Physiological levels of poly(ADP-ribose) during the cell cycle regulate HeLa cell proliferation.

Pub. Date : 2022 Aug 1

PMID : 35447104






1 Functional Relationships(s)
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1 Under normal condition in the absence of exogenous DNA-damaging agent, PAR turnovers with a half-life of <40 s; consistent with significant decrease of NAD+ levels in S phase, which is recovered by PARP inhibitors, and, substantiating the observed rapid turnover of PAR. NAD poly(ADP-ribose) polymerase 1 Homo sapiens