Title : An Inhibitor of Nuclear Factor-Kappa B Pathway Attenuates the Release of TGF-β1 and Inhibits the Fibrogenic Progress in a Model of Airway Remodeling Induced by Acrolein.

Pub. Date : 2022

PMID : 35432586






3 Functional Relationships(s)
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1 An active component of propolis, named caffeic acid phenethyl ester (CAPE), is recognized as an inhibitor of the NF-kappaB pathway and shows anti-inflammatory effect. caffeic acid phenethyl ester nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 An active component of propolis, named caffeic acid phenethyl ester (CAPE), is recognized as an inhibitor of the NF-kappaB pathway and shows anti-inflammatory effect. caffeic acid phenethyl ester nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
3 In conclusion, as an inhibitor of the NF-kappaB pathway, CAPE attenuated the release of TGF-beta1, which inhibited the fibrogenic progress induced by acrolein in mice and took no effect on inhibiting airway mucus hypersecretion. caffeic acid phenethyl ester nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus