Title : Quercetin exerts anti-inflammatory effects via inhibiting tumor necrosis factor-α-induced matrix metalloproteinase-9 expression in normal human gastric epithelial cells.

Pub. Date : 2022 Mar 21

PMID : 35431500






2 Functional Relationships(s)
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1 Quercetin and TNF-alpha antagonists decreased the TNF-alpha-induced phosphorylation of c-Src, ERK1/2, c-Fos, and p65 in a dose- and time-dependent manner. Quercetin mitogen-activated protein kinase 3 Homo sapiens
2 CONCLUSION: Quercetin significantly downregulates TNF-alpha-induced MMP-9 expression in GES-1 cells via the TNFR-c-Src-ERK1/2 and c-Fos or NF-kappaB pathways. Quercetin mitogen-activated protein kinase 3 Homo sapiens