Title : Synthesis of benzoin under supramolecular catalysis involving cyclodextrins in water: application for the preparation of the antiepileptic drug phenytoin.

Pub. Date : 2022 Mar 31

PMID : 35424977






1 Functional Relationships(s)
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1 Among the cyclodextrins screened for the synthesis of 2-hydroxy-1,2-diphenylethanone (benzoin) in water, 2-hydroxypropyl-beta-cyclodextrin (HP-beta-CD) exhibited the highest yield in the benzoin condensation reactions, and HP-beta-CD can be recycled several times with little loss of activity through the addition of fresh VB1. Water ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens