Protein Name ACD shelterin complex subunit and telomerase recruitment factor
Organism Homo sapiens
Gene ID 65057
Gene Symbol


UniProt Q96AP0 (ACD_HUMAN), A0A590TQL1 (A0A590TQL1_HUMAN)
Relationships Total Number of functionally related compound(s) : 945
Total Number of Articles : 646

ACD shelterin complex subunit and telomerase recruitment factor

Gene Summary

This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]

  • adrenocortical dysplasia protein homolog
  • POT1 and TIN2-interacting protein
  • TIN2 interacting protein 1
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